THE MAJOR BRAIN ENDOCANNABINOID 2-AG CONTROLS NEUROPATHIC PAIN AND MECHANICAL HYPERALGESIA IN PATIENTS WITH NEUROMYELITIS OPTICA.

The major brain endocannabinoid 2-AG controls neuropathic pain and mechanical hyperalgesia in patients with neuromyelitis optica.

Recurrent myelitis is one of the predominant characteristics in patients with neuromyelitis optica (NMO).While paresis, visual loss, sensory deficits, and bladder dysfunction are well known symptoms in NMO patients, pain has been recognized only recently as another key symptom of the disease.Although spinal cord inflammation is a defining aspect of

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Output power enhancement of GaN-based flip-chip light-emitting diodes via conical structures generated by a monolayer of nanospheres

This letter describes the output power enhancement of the GaN-based flip-chip light-emitting diodes Bureau (FC LED) featuring conical structures fabricated by etching a self-assembled monolayer SiO2 spheres as the hard mask.By roughening the surface of FC LED components, it increases structural size of the Mobile Accessories components and elevates

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Real-time PCR of the mammalian hydroxymethylbilane synthase (HMBS) gene for analysis of flea (Ctenocephalides felis) feeding patterns on dogs

Abstract Background Precise data on quantitative kinetics of blood feeding of fleas, particularly immediately after contact with the host, are essential for understanding dynamics of flea-borne disease Bodysuits transmission and for evaluating flea control strategies.Standard methods used are inadequate for studies that simulate early events after

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